G298-0275 Screening compound: N-(3-chloro-4-methoxyphenyl)-3-[7-(3,4-dimethylphenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]propanamide

G298-0275 Screening compound: N-(3-chloro-4-methoxyphenyl)-3-[7-(3,4-dimethylphenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]propanamide
G298-0275 Screening compound: N-(3-chloro-4-methoxyphenyl)-3-[7-(3,4-dimethylphenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G298-0275
N-(3-chloro-4-methoxyphenyl)-3-[7-(3,4-dimethylphenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G298-0275

Molecular Formula

C23H22ClN5O3 (C23 H22 ClN5 O3)

Compound Name

N-(3-chloro-4-methoxyphenyl)-3-[7-(3,4-dimethylphenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]propanamide

IUPAC name

N-(3-chloro-4-methoxyphenyl)-3-[7-(34-dimethylphenyl)-8-oxo-7H8H-[124]triazolo[43-a]pyrazin-3-yl]propanamide

SMILES

Cc(cc1)c(C)cc1N(C=Cn1c2nnc1CCC(Nc(cc1)cc(Cl)c1OC)=O)C2=O

InChI

InChI=1S/C23H22ClN5O3/c1-14-4-6-17(12-15(14)2)28-10-11-29-20(26-27-22(29)23(28)31)8-9-21(30)25-16-5-7-19(32-3)18(24)13-16/h4-7,10-13H,8-9H2,1-3H3,(H,25,30)

InChI Key

IGTPZDHEECFGQG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14995826

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

451.91

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.698

Distribution Coefficient, logD

2.698

Water Solubility, LogSw

-3.48

Polar Surface Area

69.876

Acid Dissociation Constant (pKa)

10.31

Base Dissociation Constant (pKb)

-5.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.70

G298-0275 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with G298-0275 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G298-0275?
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What is the minimum amount of G298-0275 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G298-0275
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G298-0275
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G298-0275 available by request