G298-0426 Screening compound: N-[2-(1H-indol-3-yl)ethyl]-3-[7-(4-methoxyphenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]propanamide

G298-0426 Screening compound: N-[2-(1H-indol-3-yl)ethyl]-3-[7-(4-methoxyphenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]propanamide
G298-0426 Screening compound: N-[2-(1H-indol-3-yl)ethyl]-3-[7-(4-methoxyphenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G298-0426
N-[2-(1H-indol-3-yl)ethyl]-3-[7-(4-methoxyphenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G298-0426

Molecular Formula

C25H24N6O3 (C25 H24 N6 O3)

Compound Name

N-[2-(1H-indol-3-yl)ethyl]-3-[7-(4-methoxyphenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]propanamide

IUPAC name

N-[2-(1H-indol-3-yl)ethyl]-3-[7-(4-methoxyphenyl)-8-oxo-7H8H-[124]triazolo[43-a]pyrazin-3-yl]propanamide

SMILES

COc(cc1)ccc1N(C=Cn1c2nnc1CCC(NCCc1c[nH]c3c1cccc3)=O)C2=O

InChI

InChI=1S/C25H24N6O3/c1-34-19-8-6-18(7-9-19)30-14-15-31-22(28-29-24(31)25(30)33)10-11-23(32)26-13-12-17-16-27-21-5-3-2-4-20(17)21/h2-9,14-16,27H,10-13H2,1H3,(H,26,32)

InChI Key

AMVCBEXGSNMDBE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14995942

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

456.5

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

0.849

Distribution Coefficient, logD

0.849

Water Solubility, LogSw

-1.90

Polar Surface Area

80.824

Acid Dissociation Constant (pKa)

14.31

Base Dissociation Constant (pKb)

-4.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

G298-0426 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with G298-0426 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G298-0426?
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What is the minimum amount of G298-0426 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G298-0426
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G298-0426
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G298-0426 available by request