G300-1248 Screening compound: 2-{8-ethoxy-3-oxo-2-phenyl-1H,2H,3H,4H-chromeno[2,3-c]pyrazol-1-yl}-N-[3-(trifluoromethyl)phenyl]acetamide

G300-1248 Screening compound: 2-{8-ethoxy-3-oxo-2-phenyl-1H,2H,3H,4H-chromeno[2,3-c]pyrazol-1-yl}-N-[3-(trifluoromethyl)phenyl]acetamide
G300-1248 Screening compound: 2-{8-ethoxy-3-oxo-2-phenyl-1H,2H,3H,4H-chromeno[2,3-c]pyrazol-1-yl}-N-[3-(trifluoromethyl)phenyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G300-1248
2-{8-ethoxy-3-oxo-2-phenyl-1H,2H,3H,4H-chromeno[2,3-c]pyrazol-1-yl}-N-[3-(trifluoromethyl)phenyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G300-1248

Molecular Formula

C27H22F3N3O4 (C27 H22 F3 N3 O4)

Compound Name

2-{8-ethoxy-3-oxo-2-phenyl-1H,2H,3H,4H-chromeno[2,3-c]pyrazol-1-yl}-N-[3-(trifluoromethyl)phenyl]acetamide

IUPAC name

2-{8-ethoxy-3-oxo-2-phenyl-1H2H3H4H-chromeno[23-c]pyrazol-1-yl}-N-[3-(trifluoromethyl)phenyl]acetamide

SMILES

CCOc(cccc1C2)c1OC(N(CC(Nc1cccc(C(F)(F)F)c1)=O)N1c3ccccc3)=C2C1=O

InChI

InChI=1S/C27H22F3N3O4/c1-2-36-22-13-6-8-17-14-21-25(35)33(20-11-4-3-5-12-20)32(26(21)37-24(17)22)16-23(34)31-19-10-7-9-18(15-19)27(28,29)30/h3-13,15H,2,14,16H2,1H3,(H,31,34)

InChI Key

YNYYUOJPYWIVCL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27213784

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

509.48

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.633

Distribution Coefficient, logD

5.633

Water Solubility, LogSw

-5.50

Polar Surface Area

56.370

Acid Dissociation Constant (pKa)

10.85

Base Dissociation Constant (pKb)

-1.14

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.50

G300-1248 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with G300-1248 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G300-1248?
Check Price and Availability of G300-1248, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G300-1248 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G300-1248
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G300-1248
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G300-1248 available by request