G305-0489 Screening compound: 6-chloro-3-{2-[4-(2,5-dimethylphenyl)piperazin-1-yl]-2-oxoethyl}-2,3-dihydro-1,3-benzoxazol-2-one

G305-0489 Screening compound: 6-chloro-3-{2-[4-(2,5-dimethylphenyl)piperazin-1-yl]-2-oxoethyl}-2,3-dihydro-1,3-benzoxazol-2-one
G305-0489 Screening compound: 6-chloro-3-{2-[4-(2,5-dimethylphenyl)piperazin-1-yl]-2-oxoethyl}-2,3-dihydro-1,3-benzoxazol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G305-0489
6-chloro-3-{2-[4-(2,5-dimethylphenyl)piperazin-1-yl]-2-oxoethyl}-2,3-dihydro-1,3-benzoxazol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G305-0489

Molecular Formula

C21H22ClN3O3 (C21 H22 ClN3 O3)

Compound Name

6-chloro-3-{2-[4-(2,5-dimethylphenyl)piperazin-1-yl]-2-oxoethyl}-2,3-dihydro-1,3-benzoxazol-2-one

IUPAC name

6-chloro-3-{2-[4-(25-dimethylphenyl)piperazin-1-yl]-2-oxoethyl}-23-dihydro-13-benzoxazol-2-one

SMILES

Cc1cc(N(CC2)CCN2C(CN(c(ccc(Cl)c2)c2O2)C2=O)=O)c(C)cc1

InChI

InChI=1S/C21H22ClN3O3/c1-14-3-4-15(2)18(11-14)23-7-9-24(10-8-23)20(26)13-25-17-6-5-16(22)12-19(17)28-21(25)27/h3-6,11-12H,7-10,13H2,1-2H3

InChI Key

PPFGMDOHVCOFNA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14996070

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

399.88

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.180

Distribution Coefficient, logD

4.180

Water Solubility, LogSw

-4.53

Polar Surface Area

42.419

Acid Dissociation Constant (pKa)

21.46

Base Dissociation Constant (pKb)

4.79

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

G305-0489 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anti-Aging Library (44940 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G305-0489 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G305-0489?
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What is the minimum amount of G305-0489 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G305-0489
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G305-0489
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G305-0489 available by request