G305-0579 Screening compound: 6-chloro-3-{2-[4-(4-methoxyphenyl)piperazin-1-yl]-2-oxoethyl}-2,3-dihydro-1,3-benzoxazol-2-one

G305-0579 Screening compound: 6-chloro-3-{2-[4-(4-methoxyphenyl)piperazin-1-yl]-2-oxoethyl}-2,3-dihydro-1,3-benzoxazol-2-one
G305-0579 Screening compound: 6-chloro-3-{2-[4-(4-methoxyphenyl)piperazin-1-yl]-2-oxoethyl}-2,3-dihydro-1,3-benzoxazol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G305-0579
6-chloro-3-{2-[4-(4-methoxyphenyl)piperazin-1-yl]-2-oxoethyl}-2,3-dihydro-1,3-benzoxazol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G305-0579

Molecular Formula

C20H20ClN3O4 (C20 H20 ClN3 O4)

Compound Name

6-chloro-3-{2-[4-(4-methoxyphenyl)piperazin-1-yl]-2-oxoethyl}-2,3-dihydro-1,3-benzoxazol-2-one

IUPAC name

6-chloro-3-{2-[4-(4-methoxyphenyl)piperazin-1-yl]-2-oxoethyl}-23-dihydro-13-benzoxazol-2-one

SMILES

COc(cc1)ccc1N(CC1)CCN1C(CN(c(ccc(Cl)c1)c1O1)C1=O)=O

InChI

InChI=1S/C20H20ClN3O4/c1-27-16-5-3-15(4-6-16)22-8-10-23(11-9-22)19(25)13-24-17-7-2-14(21)12-18(17)28-20(24)26/h2-7,12H,8-11,13H2,1H3

InChI Key

INQDMFQYUNYTKQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD13596756

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

401.85

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.126

Distribution Coefficient, logD

3.126

Water Solubility, LogSw

-3.62

Polar Surface Area

50.264

Acid Dissociation Constant (pKa)

21.46

Base Dissociation Constant (pKb)

7.19

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.00

G305-0579 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Immune system
Mechanism of action:
  • Epigenetic
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G305-0579 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G305-0579?
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What is the minimum amount of G305-0579 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G305-0579
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G305-0579
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G305-0579 available by request