G305-1251 Screening compound: N-(2,4-difluorophenyl)-1-[(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)sulfonyl]piperidine-3-carboxamide

G305-1251 Screening compound: N-(2,4-difluorophenyl)-1-[(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)sulfonyl]piperidine-3-carboxamide
G305-1251 Screening compound: N-(2,4-difluorophenyl)-1-[(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)sulfonyl]piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G305-1251
N-(2,4-difluorophenyl)-1-[(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)sulfonyl]piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G305-1251

Molecular Formula

C19H17F2N3O5S (C19 H17 F2 N3 O5 S)

Compound Name

N-(2,4-difluorophenyl)-1-[(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)sulfonyl]piperidine-3-carboxamide

IUPAC name

N-(24-difluorophenyl)-1-[(2-oxo-23-dihydro-13-benzoxazol-6-yl)sulfonyl]piperidine-3-carboxamide

SMILES

O=C(C(CCC1)CN1S(c(cc1)cc(O2)c1NC2=O)(=O)=O)Nc(ccc(F)c1)c1F

InChI

InChI=1S/C19H17F2N3O5S/c20-12-3-5-15(14(21)8-12)22-18(25)11-2-1-7-24(10-11)30(27,28)13-4-6-16-17(9-13)29-19(26)23-16/h3-6,8-9,11H,1-2,7,10H2,(H,22,25)(H,23,26)/t11-/m0/s1

InChI Key

GDLGZGMNLJFFPT-NSHDSACASA-N

MDL Number (MFCD)

MFCD14996143

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

437.42

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.212

Distribution Coefficient, logD

2.058

Water Solubility, LogSw

-2.90

Polar Surface Area

87.694

Acid Dissociation Constant (pKa)

7.77

Base Dissociation Constant (pKb)

-2.40

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

26.30

G305-1251 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G305-1251 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G305-1251?
Check Price and Availability of G305-1251, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G305-1251 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G305-1251
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G305-1251
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G305-1251 available by request