G305-1347 Screening compound: N-(2H-1,3-benzodioxol-5-yl)-1-[(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)sulfonyl]piperidine-3-carboxamide

G305-1347 Screening compound: N-(2H-1,3-benzodioxol-5-yl)-1-[(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)sulfonyl]piperidine-3-carboxamide
G305-1347 Screening compound: N-(2H-1,3-benzodioxol-5-yl)-1-[(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)sulfonyl]piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G305-1347
N-(2H-1,3-benzodioxol-5-yl)-1-[(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)sulfonyl]piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G305-1347

Molecular Formula

C20H19N3O7S (C20 H19 N3 O7 S)

Compound Name

N-(2H-1,3-benzodioxol-5-yl)-1-[(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)sulfonyl]piperidine-3-carboxamide

IUPAC name

N-(2H-13-benzodioxol-5-yl)-1-[(2-oxo-23-dihydro-13-benzoxazol-6-yl)sulfonyl]piperidine-3-carboxamide

SMILES

O=C(C(CCC1)CN1S(c(cc1)cc(O2)c1NC2=O)(=O)=O)Nc(cc1)cc2c1OCO2

InChI

InChI=1S/C20H19N3O7S/c24-19(21-13-3-6-16-18(8-13)29-11-28-16)12-2-1-7-23(10-12)31(26,27)14-4-5-15-17(9-14)30-20(25)22-15/h3-6,8-9,12H,1-2,7,10-11H2,(H,21,24)(H,22,25)/t12-/m0/s1

InChI Key

UKALMJHVAZMUAD-LBPRGKRZSA-N

MDL Number (MFCD)

MFCD14996174

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

445.45

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.830

Distribution Coefficient, logD

1.797

Water Solubility, LogSw

-2.61

Polar Surface Area

105.507

Acid Dissociation Constant (pKa)

8.49

Base Dissociation Constant (pKb)

0.28

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

30.00

G305-1347 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Kinases
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G305-1347 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G305-1347?
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What is the minimum amount of G305-1347 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G305-1347
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G305-1347
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G305-1347 available by request