G305-1364 Screening compound: ethyl 4-{1-[(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)sulfonyl]piperidine-3-amido}piperidine-1-carboxylate

G305-1364 Screening compound: ethyl 4-{1-[(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)sulfonyl]piperidine-3-amido}piperidine-1-carboxylate
G305-1364 Screening compound: ethyl 4-{1-[(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)sulfonyl]piperidine-3-amido}piperidine-1-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound G305-1364
ethyl 4-{1-[(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)sulfonyl]piperidine-3-amido}piperidine-1-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G305-1364

Molecular Formula

C21H28N4O7S (C21 H28 N4 O7 S)

Compound Name

ethyl 4-{1-[(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)sulfonyl]piperidine-3-amido}piperidine-1-carboxylate

IUPAC name

ethyl 4-{1-[(2-oxo-23-dihydro-13-benzoxazol-6-yl)sulfonyl]piperidine-3-amido}piperidine-1-carboxylate

SMILES

CCOC(N(CC1)CCC1NC(C(CCC1)CN1S(c(cc1)cc(O2)c1NC2=O)(=O)=O)=O)=O

InChI

InChI=1S/C21H28N4O7S/c1-2-31-21(28)24-10-7-15(8-11-24)22-19(26)14-4-3-9-25(13-14)33(29,30)16-5-6-17-18(12-16)32-20(27)23-17/h5-6,12,14-15H,2-4,7-11,13H2,1H3,(H,22,26)(H,23,27)/t14-/m0/s1

InChI Key

VBHMXIOEJKIUBK-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD14996178

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

480.54

Hydrogen Bond Acceptors Count

13.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

11

Partition Coefficient, logP

1.190

Distribution Coefficient, logD

1.157

Water Solubility, LogSw

-2.48

Polar Surface Area

112.219

Acid Dissociation Constant (pKa)

8.49

Base Dissociation Constant (pKb)

0.73

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

57.10

G305-1364 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G305-1364 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G305-1364?
Check Price and Availability of G305-1364, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G305-1364 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G305-1364
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G305-1364
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G305-1364 available by request