G307-1757 Screening compound: 2-[4-(morpholine-4-sulfonyl)-1H-imidazol-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide

G307-1757 Screening compound: 2-[4-(morpholine-4-sulfonyl)-1H-imidazol-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide
G307-1757 Screening compound: 2-[4-(morpholine-4-sulfonyl)-1H-imidazol-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G307-1757
2-[4-(morpholine-4-sulfonyl)-1H-imidazol-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G307-1757

Molecular Formula

C19H24N4O4S (C19 H24 N4 O4 S)

Compound Name

2-[4-(morpholine-4-sulfonyl)-1H-imidazol-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide

IUPAC name

2-[4-(morpholine-4-sulfonyl)-1H-imidazol-1-yl]-N-(1234-tetrahydronaphthalen-1-yl)acetamide

SMILES

O=C(Cn1cnc(S(N2CCOCC2)(=O)=O)c1)NC(CCC1)c2c1cccc2

InChI

InChI=1S/C19H24N4O4S/c24-18(21-17-7-3-5-15-4-1-2-6-16(15)17)12-22-13-19(20-14-22)28(25,26)23-8-10-27-11-9-23/h1-2,4,6,13-14,17H,3,5,7-12H2,(H,21,24)/t17-/m0/s1

InChI Key

DOBPQQCJSGMHJE-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD14996703

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

404.49

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.311

Distribution Coefficient, logD

1.311

Water Solubility, LogSw

-2.35

Polar Surface Area

76.011

Acid Dissociation Constant (pKa)

11.98

Base Dissociation Constant (pKb)

-0.50

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

47.40

G307-1757 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G307-1757 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G307-1757?
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What is the minimum amount of G307-1757 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G307-1757
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G307-1757
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G307-1757 available by request