G307-2848 Screening compound: N-(5-chloro-2,4-dimethoxyphenyl)-2-[4-(2,3-dihydro-1H-indole-1-sulfonyl)-1H-imidazol-1-yl]acetamide

G307-2848 Screening compound: N-(5-chloro-2,4-dimethoxyphenyl)-2-[4-(2,3-dihydro-1H-indole-1-sulfonyl)-1H-imidazol-1-yl]acetamide
G307-2848 Screening compound: N-(5-chloro-2,4-dimethoxyphenyl)-2-[4-(2,3-dihydro-1H-indole-1-sulfonyl)-1H-imidazol-1-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G307-2848
N-(5-chloro-2,4-dimethoxyphenyl)-2-[4-(2,3-dihydro-1H-indole-1-sulfonyl)-1H-imidazol-1-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G307-2848

Molecular Formula

C21H21ClN4O5S (C21 H21 ClN4 O5 S)

Compound Name

N-(5-chloro-2,4-dimethoxyphenyl)-2-[4-(2,3-dihydro-1H-indole-1-sulfonyl)-1H-imidazol-1-yl]acetamide

IUPAC name

N-(5-chloro-24-dimethoxyphenyl)-2-[4-(23-dihydro-1H-indole-1-sulfonyl)-1H-imidazol-1-yl]acetamide

SMILES

COc(c(NC(Cn1cnc(S(N(CC2)c3c2cccc3)(=O)=O)c1)=O)c1)cc(OC)c1Cl

InChI

InChI=1S/C21H21ClN4O5S/c1-30-18-10-19(31-2)16(9-15(18)22)24-20(27)11-25-12-21(23-13-25)32(28,29)26-8-7-14-5-3-4-6-17(14)26/h3-6,9-10,12-13H,7-8,11H2,1-2H3,(H,24,27)

InChI Key

OXVGRLJKMRJUER-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14996783

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

476.94

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.784

Distribution Coefficient, logD

2.768

Water Solubility, LogSw

-3.35

Polar Surface Area

81.307

Acid Dissociation Constant (pKa)

8.83

Base Dissociation Constant (pKb)

0.67

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

G307-2848 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with G307-2848 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G307-2848?
Check Price and Availability of G307-2848, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G307-2848 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G307-2848
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G307-2848
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G307-2848 available by request