G310-0181 Screening compound: ethyl 5-(5-{[4-(pyrimidin-2-yl)piperazin-1-yl]sulfonyl}thiophen-2-yl)-1,2-oxazole-3-carboxylate

G310-0181 Screening compound: ethyl 5-(5-{[4-(pyrimidin-2-yl)piperazin-1-yl]sulfonyl}thiophen-2-yl)-1,2-oxazole-3-carboxylate
G310-0181 Screening compound: ethyl 5-(5-{[4-(pyrimidin-2-yl)piperazin-1-yl]sulfonyl}thiophen-2-yl)-1,2-oxazole-3-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound G310-0181
ethyl 5-(5-{[4-(pyrimidin-2-yl)piperazin-1-yl]sulfonyl}thiophen-2-yl)-1,2-oxazole-3-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G310-0181

Molecular Formula

C18H19N5O5S2 (C18 H19 N5 O5 S2)

Compound Name

ethyl 5-(5-{[4-(pyrimidin-2-yl)piperazin-1-yl]sulfonyl}thiophen-2-yl)-1,2-oxazole-3-carboxylate

IUPAC name

ethyl 5-(5-{[4-(pyrimidin-2-yl)piperazin-1-yl]sulfonyl}thiophen-2-yl)-12-oxazole-3-carboxylate

SMILES

CCOC(c1noc(-c(s2)ccc2S(N(CC2)CCN2c2ncccn2)(=O)=O)c1)=O

InChI

InChI=1S/C18H19N5O5S2/c1-2-27-17(24)13-12-14(28-21-13)15-4-5-16(29-15)30(25,26)23-10-8-22(9-11-23)18-19-6-3-7-20-18/h3-7,12H,2,8-11H2,1H3

InChI Key

UQLLIRFSECRFSJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14996965

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

449.51

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.916

Distribution Coefficient, logD

2.916

Water Solubility, LogSw

-3.31

Polar Surface Area

96.879

Acid Dissociation Constant (pKa)

20.87

Base Dissociation Constant (pKb)

3.11

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

G310-0181 in Drug Discovery

Included in Screening Libraries

Integrin Receptors Targeted library (1715 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Immune system
Targets:
  • Others

References: we are preparing a list of scientific research reports with G310-0181 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G310-0181?
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What is the minimum amount of G310-0181 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G310-0181
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G310-0181
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G310-0181 available by request