G319-0164 Screening compound: N-(5-chloro-2-methoxyphenyl)-3-phenyl-2-(quinoline-8-sulfonamido)propanamide

G319-0164 Screening compound: N-(5-chloro-2-methoxyphenyl)-3-phenyl-2-(quinoline-8-sulfonamido)propanamide
G319-0164 Screening compound: N-(5-chloro-2-methoxyphenyl)-3-phenyl-2-(quinoline-8-sulfonamido)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G319-0164
N-(5-chloro-2-methoxyphenyl)-3-phenyl-2-(quinoline-8-sulfonamido)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G319-0164

Molecular Formula

C25H22ClN3O4S (C25 H22 ClN3 O4 S)

Compound Name

N-(5-chloro-2-methoxyphenyl)-3-phenyl-2-(quinoline-8-sulfonamido)propanamide

IUPAC name

N-(5-chloro-2-methoxyphenyl)-3-phenyl-2-(quinoline-8-sulfonamido)propanamide

SMILES

COc(ccc(Cl)c1)c1NC(C(Cc1ccccc1)NS(c1cccc2cccnc12)(=O)=O)=O

InChI

InChI=1S/C25H22ClN3O4S/c1-33-22-13-12-19(26)16-20(22)28-25(30)21(15-17-7-3-2-4-8-17)29-34(31,32)23-11-5-9-18-10-6-14-27-24(18)23/h2-14,16,21,29H,15H2,1H3,(H,28,30)/t21-/m0/s1

InChI Key

PHDNRMIXEXGLFJ-NRFANRHFSA-N

MDL Number (MFCD)

MFCD14997453

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

495.99

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.208

Distribution Coefficient, logD

4.073

Water Solubility, LogSw

-4.46

Polar Surface Area

81.398

Acid Dissociation Constant (pKa)

7.84

Base Dissociation Constant (pKb)

-0.89

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

12.00

G319-0164 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

SH2 Library (10483 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Others
  • Proteases
Mechanism of action:
  • Epigenetic
  • PPI modulators

References: we are preparing a list of scientific research reports with G319-0164 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G319-0164?
Check Price and Availability of G319-0164, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G319-0164 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G319-0164
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G319-0164
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G319-0164 available by request