G323-0497 Screening compound: 1-({3-methyl-5-[(1E)-2-(thiophen-2-yl)ethenyl]-1,2-oxazol-4-yl}sulfonyl)-N-[(4-methylphenyl)methyl]piperidine-3-carboxamide

G323-0497 Screening compound: 1-({3-methyl-5-[(1E)-2-(thiophen-2-yl)ethenyl]-1,2-oxazol-4-yl}sulfonyl)-N-[(4-methylphenyl)methyl]piperidine-3-carboxamide
G323-0497 Screening compound: 1-({3-methyl-5-[(1E)-2-(thiophen-2-yl)ethenyl]-1,2-oxazol-4-yl}sulfonyl)-N-[(4-methylphenyl)methyl]piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G323-0497
1-({3-methyl-5-[(1E)-2-(thiophen-2-yl)ethenyl]-1,2-oxazol-4-yl}sulfonyl)-N-[(4-methylphenyl)methyl]piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G323-0497

Molecular Formula

C24H27N3O4S2 (C24 H27 N3 O4 S2)

Compound Name

1-({3-methyl-5-[(1E)-2-(thiophen-2-yl)ethenyl]-1,2-oxazol-4-yl}sulfonyl)-N-[(4-methylphenyl)methyl]piperidine-3-carboxamide

IUPAC name

1-({3-methyl-5-[(1E)-2-(thiophen-2-yl)ethenyl]-12-oxazol-4-yl}sulfonyl)-N-[(4-methylphenyl)methyl]piperidine-3-carboxamide

SMILES

Cc1noc(/C=C/c2cccs2)c1S(N(CCC1)CC1C(NCc1ccc(C)cc1)=O)(=O)=O

InChI

InChI=1S/C24H27N3O4S2/c1-17-7-9-19(10-8-17)15-25-24(28)20-5-3-13-27(16-20)33(29,30)23-18(2)26-31-22(23)12-11-21-6-4-14-32-21/h4,6-12,14,20H,3,5,13,15-16H2,1-2H3,(H,25,28)/t20-/m0/s1

InChI Key

IWMIECJJLLWHAW-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD14997528

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

485.63

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.041

Distribution Coefficient, logD

3.041

Water Solubility, LogSw

-3.29

Polar Surface Area

78.830

Acid Dissociation Constant (pKa)

11.94

Base Dissociation Constant (pKb)

-2.02

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

33.30

G323-0497 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • GPCR
  • Others
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with G323-0497 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G323-0497?
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What is the minimum amount of G323-0497 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G323-0497
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G323-0497
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G323-0497 available by request