G325-0461 Screening compound: 3-[(1-cyclopropanecarbonyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-N-(2-fluorophenyl)propanamide

G325-0461 Screening compound: 3-[(1-cyclopropanecarbonyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-N-(2-fluorophenyl)propanamide
G325-0461 Screening compound: 3-[(1-cyclopropanecarbonyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-N-(2-fluorophenyl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G325-0461
3-[(1-cyclopropanecarbonyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-N-(2-fluorophenyl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G325-0461

Molecular Formula

C21H21FN2O4S (C21 H21 FN2 O4 S)

Compound Name

3-[(1-cyclopropanecarbonyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-N-(2-fluorophenyl)propanamide

IUPAC name

3-[(1-cyclopropanecarbonyl-23-dihydro-1H-indol-5-yl)sulfonyl]-N-(2-fluorophenyl)propanamide

SMILES

O=C(CCS(c(cc1)cc(CC2)c1N2C(C1CC1)=O)(=O)=O)Nc(cccc1)c1F

InChI

InChI=1S/C21H21FN2O4S/c22-17-3-1-2-4-18(17)23-20(25)10-12-29(27,28)16-7-8-19-15(13-16)9-11-24(19)21(26)14-5-6-14/h1-4,7-8,13-14H,5-6,9-12H2,(H,23,25)

InChI Key

ZRVLXHSSLGPHFJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14997589

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

416.47

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.240

Distribution Coefficient, logD

2.239

Water Solubility, LogSw

-3.02

Polar Surface Area

67.657

Acid Dissociation Constant (pKa)

9.88

Base Dissociation Constant (pKb)

-1.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

G325-0461 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with G325-0461 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G325-0461?
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What is the minimum amount of G325-0461 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G325-0461
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G325-0461
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G325-0461 available by request