G336-0130 Screening compound: 2-(4-chlorophenoxy)-1-(4-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperazin-1-yl)ethan-1-one

G336-0130 Screening compound: 2-(4-chlorophenoxy)-1-(4-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperazin-1-yl)ethan-1-one
G336-0130 Screening compound: 2-(4-chlorophenoxy)-1-(4-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperazin-1-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G336-0130
2-(4-chlorophenoxy)-1-(4-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperazin-1-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G336-0130

Molecular Formula

C18H17ClN4O2S (C18 H17 ClN4 O2 S)

Compound Name

2-(4-chlorophenoxy)-1-(4-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperazin-1-yl)ethan-1-one

IUPAC name

2-(4-chlorophenoxy)-1-(4-{[13]thiazolo[54-b]pyridin-2-yl}piperazin-1-yl)ethan-1-one

SMILES

O=C(COc(cc1)ccc1Cl)N(CC1)CCN1c1nc(cccn2)c2s1

InChI

InChI=1S/C18H17ClN4O2S/c19-13-3-5-14(6-4-13)25-12-16(24)22-8-10-23(11-9-22)18-21-15-2-1-7-20-17(15)26-18/h1-7H,8-12H2

InChI Key

NDKLYTQSNIXQGL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27135728

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

388.88

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.064

Distribution Coefficient, logD

3.064

Water Solubility, LogSw

-3.37

Polar Surface Area

46.060

Acid Dissociation Constant (pKa)

22.83

Base Dissociation Constant (pKb)

7.95

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

G336-0130 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Therapeutical areas:
  • Immune system
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with G336-0130 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G336-0130?
Check Price and Availability of G336-0130, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G336-0130 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G336-0130
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G336-0130
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G336-0130 available by request