G340-0376 Screening compound: 1-benzyl-4-(1-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperidine-4-carbonyl)piperazine

G340-0376 Screening compound: 1-benzyl-4-(1-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperidine-4-carbonyl)piperazine
G340-0376 Screening compound: 1-benzyl-4-(1-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperidine-4-carbonyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G340-0376
1-benzyl-4-(1-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperidine-4-carbonyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G340-0376

Molecular Formula

C23H27N5OS (C23 H27 N5 OS)

Compound Name

1-benzyl-4-(1-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperidine-4-carbonyl)piperazine

IUPAC name

1-benzyl-4-(1-{[13]thiazolo[54-b]pyridin-2-yl}piperidine-4-carbonyl)piperazine

SMILES

O=C(C(CC1)CCN1c1nc2cccnc2s1)N1CCN(Cc2ccccc2)CC1

InChI

InChI=1S/C23H27N5OS/c29-22(27-15-13-26(14-16-27)17-18-5-2-1-3-6-18)19-8-11-28(12-9-19)23-25-20-7-4-10-24-21(20)30-23/h1-7,10,19H,8-9,11-17H2

InChI Key

UDWHUXBRDYSLGN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14999112

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.57

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.131

Distribution Coefficient, logD

3.079

Water Solubility, LogSw

-3.01

Polar Surface Area

42.821

Acid Dissociation Constant (pKa)

20.97

Base Dissociation Constant (pKb)

6.50

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

43.50

G340-0376 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

GPCR Targeted Library (31838 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with G340-0376 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G340-0376?
Check Price and Availability of G340-0376, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G340-0376 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G340-0376
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G340-0376
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G340-0376 available by request