G340-0436 Screening compound: N-cyclopentyl-1-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperidine-4-carboxamide

G340-0436 Screening compound: N-cyclopentyl-1-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperidine-4-carboxamide
G340-0436 Screening compound: N-cyclopentyl-1-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G340-0436
N-cyclopentyl-1-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G340-0436

Molecular Formula

C17H22N4OS (C17 H22 N4 OS)

Compound Name

N-cyclopentyl-1-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperidine-4-carboxamide

IUPAC name

N-cyclopentyl-1-{[13]thiazolo[54-b]pyridin-2-yl}piperidine-4-carboxamide

SMILES

O=C(C(CC1)CCN1c1nc2cccnc2s1)NC1CCCC1

InChI

InChI=1S/C17H22N4OS/c22-15(19-13-4-1-2-5-13)12-7-10-21(11-8-12)17-20-14-6-3-9-18-16(14)23-17/h3,6,9,12-13H,1-2,4-5,7-8,10-11H2,(H,19,22)

InChI Key

MEIHYUUETDUUED-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14999136

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

330.45

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.897

Distribution Coefficient, logD

2.860

Water Solubility, LogSw

-3.18

Polar Surface Area

47.137

Acid Dissociation Constant (pKa)

15.70

Base Dissociation Constant (pKb)

11.73

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

58.80

G340-0436 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with G340-0436 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G340-0436?
Check Price and Availability of G340-0436, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G340-0436 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G340-0436
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G340-0436
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G340-0436 available by request