G340-0630 Screening compound: N-[(2,5-dimethoxyphenyl)methyl]-1-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperidine-4-carboxamide

G340-0630 Screening compound: N-[(2,5-dimethoxyphenyl)methyl]-1-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperidine-4-carboxamide
G340-0630 Screening compound: N-[(2,5-dimethoxyphenyl)methyl]-1-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G340-0630
N-[(2,5-dimethoxyphenyl)methyl]-1-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G340-0630

Molecular Formula

C21H24N4O3S (C21 H24 N4 O3 S)

Compound Name

N-[(2,5-dimethoxyphenyl)methyl]-1-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperidine-4-carboxamide

IUPAC name

N-[(25-dimethoxyphenyl)methyl]-1-{[13]thiazolo[54-b]pyridin-2-yl}piperidine-4-carboxamide

SMILES

COc(cc1)cc(CNC(C(CC2)CCN2c2nc3cccnc3s2)=O)c1OC

InChI

InChI=1S/C21H24N4O3S/c1-27-16-5-6-18(28-2)15(12-16)13-23-19(26)14-7-10-25(11-8-14)21-24-17-4-3-9-22-20(17)29-21/h3-6,9,12,14H,7-8,10-11,13H2,1-2H3,(H,23,26)

InChI Key

YVBUBEQGTZCIIL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14999219

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

412.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.101

Distribution Coefficient, logD

3.065

Water Solubility, LogSw

-3.27

Polar Surface Area

62.220

Acid Dissociation Constant (pKa)

13.07

Base Dissociation Constant (pKb)

11.73

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.10

G340-0630 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with G340-0630 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G340-0630?
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What is the minimum amount of G340-0630 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G340-0630
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G340-0630
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G340-0630 available by request