G340-0847 Screening compound: ethyl 2-(2-{[(1-[1,3]thiazolo[5,4-b]pyridin-2-yl-3-piperidyl)carbonyl]amino}-1,3-thiazol-4-yl)acetate

G340-0847 Screening compound: ethyl 2-(2-{[(1-[1,3]thiazolo[5,4-b]pyridin-2-yl-3-piperidyl)carbonyl]amino}-1,3-thiazol-4-yl)acetate
G340-0847 Screening compound: ethyl 2-(2-{[(1-[1,3]thiazolo[5,4-b]pyridin-2-yl-3-piperidyl)carbonyl]amino}-1,3-thiazol-4-yl)acetate alternative view

Chemical Structure Depiction of ChemDiv screening compound G340-0847
ethyl 2-(2-{[(1-[1,3]thiazolo[5,4-b]pyridin-2-yl-3-piperidyl)carbonyl]amino}-1,3-thiazol-4-yl)acetate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G340-0847

Molecular Formula

C19H21N5O3S2 (C19 H21 N5 O3 S2)

Compound Name

ethyl 2-(2-{[(1-[1,3]thiazolo[5,4-b]pyridin-2-yl-3-piperidyl)carbonyl]amino}-1,3-thiazol-4-yl)acetate

IUPAC name

ethyl 2-[2-(1-{[13]thiazolo[54-b]pyridin-2-yl}piperidine-3-amido)-13-thiazol-4-yl]acetate

SMILES

CCOC(Cc1csc(NC(C(CCC2)CN2c2nc3cccnc3s2)=O)n1)=O

InChI

InChI=1S/C19H21N5O3S2/c1-2-27-15(25)9-13-11-28-18(21-13)23-16(26)12-5-4-8-24(10-12)19-22-14-6-3-7-20-17(14)29-19/h3,6-7,11-12H,2,4-5,8-10H2,1H3,(H,21,23,26)/t12-/m0/s1

InChI Key

UOXQJPQMIKUALV-LBPRGKRZSA-N

MDL Number (MFCD)

MFCD14999295

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

431.54

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.178

Distribution Coefficient, logD

3.165

Water Solubility, LogSw

-3.18

Polar Surface Area

76.357

Acid Dissociation Constant (pKa)

8.97

Base Dissociation Constant (pKb)

5.07

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

42.10

G340-0847 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with G340-0847 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G340-0847?
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What is the minimum amount of G340-0847 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G340-0847
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G340-0847
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G340-0847 available by request