G340-0867 Screening compound: N-[2-(4-sulfamoylphenyl)ethyl]-1-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperidine-3-carboxamide

G340-0867 Screening compound: N-[2-(4-sulfamoylphenyl)ethyl]-1-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperidine-3-carboxamide
G340-0867 Screening compound: N-[2-(4-sulfamoylphenyl)ethyl]-1-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G340-0867
N-[2-(4-sulfamoylphenyl)ethyl]-1-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G340-0867

Molecular Formula

C20H23N5O3S2 (C20 H23 N5 O3 S2)

Compound Name

N-[2-(4-sulfamoylphenyl)ethyl]-1-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperidine-3-carboxamide

IUPAC name

N-[2-(4-sulfamoylphenyl)ethyl]-1-{[13]thiazolo[54-b]pyridin-2-yl}piperidine-3-carboxamide

SMILES

NS(c1ccc(CCNC(C(CCC2)CN2c2nc(cccn3)c3s2)=O)cc1)(=O)=O

InChI

InChI=1S/C20H23N5O3S2/c21-30(27,28)16-7-5-14(6-8-16)9-11-22-18(26)15-3-2-12-25(13-15)20-24-17-4-1-10-23-19(17)29-20/h1,4-8,10,15H,2-3,9,11-13H2,(H,22,26)(H2,21,27,28)/t15-/m0/s1

InChI Key

XMYHMBDZUPFHNH-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD27136328

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

445.57

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.418

Distribution Coefficient, logD

1.415

Water Solubility, LogSw

-2.31

Polar Surface Area

97.423

Acid Dissociation Constant (pKa)

10.18

Base Dissociation Constant (pKb)

5.03

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

35.00

G340-0867 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Carbonic Anhydrase II Library (4939 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G340-0867 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G340-0867?
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What is the minimum amount of G340-0867 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G340-0867
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G340-0867
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G340-0867 available by request