G340-0954 Screening compound: N-{[4-(dimethylamino)phenyl]methyl}-1-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperidine-3-carboxamide

G340-0954 Screening compound: N-{[4-(dimethylamino)phenyl]methyl}-1-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperidine-3-carboxamide
G340-0954 Screening compound: N-{[4-(dimethylamino)phenyl]methyl}-1-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G340-0954
N-{[4-(dimethylamino)phenyl]methyl}-1-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G340-0954

Molecular Formula

C21H25N5OS (C21 H25 N5 OS)

Compound Name

N-{[4-(dimethylamino)phenyl]methyl}-1-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperidine-3-carboxamide

IUPAC name

N-{[4-(dimethylamino)phenyl]methyl}-1-{[13]thiazolo[54-b]pyridin-2-yl}piperidine-3-carboxamide

SMILES

CN(C)c1ccc(CNC(C(CCC2)CN2c2nc3cccnc3s2)=O)cc1

InChI

InChI=1S/C21H25N5OS/c1-25(2)17-9-7-15(8-10-17)13-23-19(27)16-5-4-12-26(14-16)21-24-18-6-3-11-22-20(18)28-21/h3,6-11,16H,4-5,12-14H2,1-2H3,(H,23,27)/t16-/m0/s1

InChI Key

NWACUBCVMBDJQX-INIZCTEOSA-N

MDL Number (MFCD)

MFCD27136352

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

395.53

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.974

Distribution Coefficient, logD

2.958

Water Solubility, LogSw

-3.16

Polar Surface Area

49.783

Acid Dissociation Constant (pKa)

13.36

Base Dissociation Constant (pKb)

5.96

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

38.10

G340-0954 in Drug Discovery

Included in Screening Libraries

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G340-0954 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G340-0954?
Check Price and Availability of G340-0954, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G340-0954 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G340-0954
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G340-0954
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G340-0954 available by request