G345-0227 Screening compound: 4-[(1-{[(4-acetylphenyl)carbamoyl]methyl}-6,7-dimethoxy-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)methyl]-N-methylbenzamide

G345-0227 Screening compound: 4-[(1-{[(4-acetylphenyl)carbamoyl]methyl}-6,7-dimethoxy-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)methyl]-N-methylbenzamide
G345-0227 Screening compound: 4-[(1-{[(4-acetylphenyl)carbamoyl]methyl}-6,7-dimethoxy-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)methyl]-N-methylbenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G345-0227
4-[(1-{[(4-acetylphenyl)carbamoyl]methyl}-6,7-dimethoxy-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)methyl]-N-methylbenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G345-0227

Molecular Formula

C29H28N4O7 (C29 H28 N4 O7)

Compound Name

4-[(1-{[(4-acetylphenyl)carbamoyl]methyl}-6,7-dimethoxy-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)methyl]-N-methylbenzamide

IUPAC name

4-[(1-{[(4-acetylphenyl)carbamoyl]methyl}-67-dimethoxy-24-dioxo-1234-tetrahydroquinazolin-3-yl)methyl]-N-methylbenzamide

SMILES

CC(c(cc1)ccc1NC(CN(c(cc(c(OC)c1)OC)c1C(N1Cc(cc2)ccc2C(NC)=O)=O)C1=O)=O)=O

InChI

InChI=1S/C29H28N4O7/c1-17(34)19-9-11-21(12-10-19)31-26(35)16-32-23-14-25(40-4)24(39-3)13-22(23)28(37)33(29(32)38)15-18-5-7-20(8-6-18)27(36)30-2/h5-14H,15-16H2,1-4H3,(H,30,36)(H,31,35)

InChI Key

MWVGRBGXMYPYHZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27136465

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

544.56

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

11

Partition Coefficient, logP

2.560

Distribution Coefficient, logD

2.560

Water Solubility, LogSw

-3.03

Polar Surface Area

108.339

Acid Dissociation Constant (pKa)

10.75

Base Dissociation Constant (pKb)

-1.42

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.70

G345-0227 in Drug Discovery

Included in Screening Libraries

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with G345-0227 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G345-0227?
Check Price and Availability of G345-0227, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G345-0227 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G345-0227
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G345-0227
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G345-0227 available by request