G345-0265 Screening compound: 4-({6,7-dimethoxy-1-[(2-methylphenyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl}methyl)-N-[(furan-2-yl)methyl]benzamide

G345-0265 Screening compound: 4-({6,7-dimethoxy-1-[(2-methylphenyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl}methyl)-N-[(furan-2-yl)methyl]benzamide
G345-0265 Screening compound: 4-({6,7-dimethoxy-1-[(2-methylphenyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl}methyl)-N-[(furan-2-yl)methyl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G345-0265
4-({6,7-dimethoxy-1-[(2-methylphenyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl}methyl)-N-[(furan-2-yl)methyl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G345-0265

Molecular Formula

C31H29N3O6 (C31 H29 N3 O6)

Compound Name

4-({6,7-dimethoxy-1-[(2-methylphenyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl}methyl)-N-[(furan-2-yl)methyl]benzamide

IUPAC name

4-({67-dimethoxy-1-[(2-methylphenyl)methyl]-24-dioxo-1234-tetrahydroquinazolin-3-yl}methyl)-N-[(furan-2-yl)methyl]benzamide

SMILES

Cc1c(CN(c(cc(c(OC)c2)OC)c2C(N2Cc(cc3)ccc3C(NCc3ccco3)=O)=O)C2=O)cccc1

InChI

InChI=1S/C31H29N3O6/c1-20-7-4-5-8-23(20)19-33-26-16-28(39-3)27(38-2)15-25(26)30(36)34(31(33)37)18-21-10-12-22(13-11-21)29(35)32-17-24-9-6-14-40-24/h4-16H,17-19H2,1-3H3,(H,32,35)

InChI Key

WMCZGDYFYKFZST-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27136487

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

539.59

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

5.558

Distribution Coefficient, logD

5.558

Water Solubility, LogSw

-5.38

Polar Surface Area

78.690

Acid Dissociation Constant (pKa)

11.42

Base Dissociation Constant (pKb)

-4.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.40

G345-0265 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with G345-0265 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G345-0265?
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What is the minimum amount of G345-0265 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G345-0265
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G345-0265
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G345-0265 available by request