G345-0718 Screening compound: 4-({1-[(3-fluorophenyl)methyl]-6,7-dimethoxy-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl}methyl)-N-(2-methoxyethyl)benzamide

G345-0718 Screening compound: 4-({1-[(3-fluorophenyl)methyl]-6,7-dimethoxy-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl}methyl)-N-(2-methoxyethyl)benzamide
G345-0718 Screening compound: 4-({1-[(3-fluorophenyl)methyl]-6,7-dimethoxy-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl}methyl)-N-(2-methoxyethyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G345-0718
4-({1-[(3-fluorophenyl)methyl]-6,7-dimethoxy-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl}methyl)-N-(2-methoxyethyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G345-0718

Molecular Formula

C28H28FN3O6 (C28 H28 FN3 O6)

Compound Name

4-({1-[(3-fluorophenyl)methyl]-6,7-dimethoxy-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl}methyl)-N-(2-methoxyethyl)benzamide

IUPAC name

4-({1-[(3-fluorophenyl)methyl]-67-dimethoxy-24-dioxo-1234-tetrahydroquinazolin-3-yl}methyl)-N-(2-methoxyethyl)benzamide

SMILES

COCCNC(c1ccc(CN(C(c(cc(c(OC)c2)OC)c2N2Cc3cccc(F)c3)=O)C2=O)cc1)=O

InChI

InChI=1S/C28H28FN3O6/c1-36-12-11-30-26(33)20-9-7-18(8-10-20)16-32-27(34)22-14-24(37-2)25(38-3)15-23(22)31(28(32)35)17-19-5-4-6-21(29)13-19/h4-10,13-15H,11-12,16-17H2,1-3H3,(H,30,33)

InChI Key

AJIREXONMYKEEY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27136690

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

521.55

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.804

Distribution Coefficient, logD

3.804

Water Solubility, LogSw

-4.06

Polar Surface Area

79.396

Acid Dissociation Constant (pKa)

13.05

Base Dissociation Constant (pKb)

-2.93

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

G345-0718 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G345-0718 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G345-0718?
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What is the minimum amount of G345-0718 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G345-0718
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G345-0718
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G345-0718 available by request