G352-0197 Screening compound: 1-[5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]-4-(pyridin-2-yl)piperazine

G352-0197 Screening compound: 1-[5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]-4-(pyridin-2-yl)piperazine
G352-0197 Screening compound: 1-[5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]-4-(pyridin-2-yl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G352-0197
1-[5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]-4-(pyridin-2-yl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G352-0197

Molecular Formula

C23H19F3N6O (C23 H19 F3 N6 O)

Compound Name

1-[5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]-4-(pyridin-2-yl)piperazine

IUPAC name

1-[5-phenyl-7-(trifluoromethyl)pyrazolo[15-a]pyrimidine-3-carbonyl]-4-(pyridin-2-yl)piperazine

SMILES

O=C(c(cnn1c(C(F)(F)F)c2)c1nc2-c1ccccc1)N(CC1)CCN1c1ncccc1

InChI

InChI=1S/C23H19F3N6O/c24-23(25,26)19-14-18(16-6-2-1-3-7-16)29-21-17(15-28-32(19)21)22(33)31-12-10-30(11-13-31)20-8-4-5-9-27-20/h1-9,14-15H,10-13H2

InChI Key

KYBNWXFFHXHLCL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27136866

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

452.44

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.295

Distribution Coefficient, logD

4.286

Water Solubility, LogSw

-4.24

Polar Surface Area

47.588

Acid Dissociation Constant (pKa)

24.69

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.70

G352-0197 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antifungal Library (16415 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
Agro:
  • Agro

References: we are preparing a list of scientific research reports with G352-0197 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G352-0197?
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What is the minimum amount of G352-0197 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G352-0197
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G352-0197
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G352-0197 available by request