G353-0071 Screening compound: 4-(4-methylphenyl)-2,3-dihydro-1H-1,5-benzodiazepin-2-one

G353-0071 Screening compound: 4-(4-methylphenyl)-2,3-dihydro-1H-1,5-benzodiazepin-2-one
G353-0071 Screening compound: 4-(4-methylphenyl)-2,3-dihydro-1H-1,5-benzodiazepin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G353-0071
4-(4-methylphenyl)-2,3-dihydro-1H-1,5-benzodiazepin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G353-0071

Molecular Formula

C16H14N2O (C16 H14 N2 O)

Compound Name

4-(4-methylphenyl)-2,3-dihydro-1H-1,5-benzodiazepin-2-one

IUPAC name

4-(4-methylphenyl)-23-dihydro-1H-15-benzodiazepin-2-one

SMILES

Cc(cc1)ccc1C(C1)=Nc(cccc2)c2NC1=O

InChI

InChI=1S/C16H14N2O/c1-11-6-8-12(9-7-11)15-10-16(19)18-14-5-3-2-4-13(14)17-15/h2-9H,10H2,1H3,(H,18,19)

InChI Key

GAOFITLRMJPSMO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09980913

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

250.3

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

1.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

2.787

Distribution Coefficient, logD

2.787

Water Solubility, LogSw

-3.28

Polar Surface Area

34.030

Acid Dissociation Constant (pKa)

12.40

Base Dissociation Constant (pKb)

0.38

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

G353-0071 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
Mechanism of action:
  • Epigenetic
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G353-0071 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G353-0071?
Check Price and Availability of G353-0071, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G353-0071 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G353-0071
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G353-0071
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G353-0071 available by request