G353-0257 Screening compound: N-(3-acetylphenyl)-2-[4-(3,4-dimethylphenyl)-2-oxo-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]acetamide

G353-0257 Screening compound: N-(3-acetylphenyl)-2-[4-(3,4-dimethylphenyl)-2-oxo-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]acetamide
G353-0257 Screening compound: N-(3-acetylphenyl)-2-[4-(3,4-dimethylphenyl)-2-oxo-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G353-0257
N-(3-acetylphenyl)-2-[4-(3,4-dimethylphenyl)-2-oxo-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G353-0257

Molecular Formula

C27H25N3O3 (C27 H25 N3 O3)

Compound Name

N-(3-acetylphenyl)-2-[4-(3,4-dimethylphenyl)-2-oxo-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]acetamide

IUPAC name

N-(3-acetylphenyl)-2-[4-(34-dimethylphenyl)-2-oxo-23-dihydro-1H-15-benzodiazepin-1-yl]acetamide

SMILES

CC(c1cccc(NC(CN(c(cccc2)c2N=C(C2)c3cc(C)c(C)cc3)C2=O)=O)c1)=O

InChI

InChI=1S/C27H25N3O3/c1-17-11-12-21(13-18(17)2)24-15-27(33)30(25-10-5-4-9-23(25)29-24)16-26(32)28-22-8-6-7-20(14-22)19(3)31/h4-14H,15-16H2,1-3H3,(H,28,32)

InChI Key

BWPVNXYYSUNSFF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27136990

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

439.51

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.752

Distribution Coefficient, logD

4.752

Water Solubility, LogSw

-4.49

Polar Surface Area

61.566

Acid Dissociation Constant (pKa)

10.79

Base Dissociation Constant (pKb)

-0.57

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.50

G353-0257 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with G353-0257 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G353-0257?
Check Price and Availability of G353-0257, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G353-0257 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G353-0257
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G353-0257
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G353-0257 available by request