G353-0321 Screening compound: ethyl 4-{2-[4-(4-methoxyphenyl)-2-oxo-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]acetamido}benzoate

G353-0321 Screening compound: ethyl 4-{2-[4-(4-methoxyphenyl)-2-oxo-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]acetamido}benzoate
G353-0321 Screening compound: ethyl 4-{2-[4-(4-methoxyphenyl)-2-oxo-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]acetamido}benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound G353-0321
ethyl 4-{2-[4-(4-methoxyphenyl)-2-oxo-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]acetamido}benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G353-0321

Molecular Formula

C27H25N3O5 (C27 H25 N3 O5)

Compound Name

ethyl 4-{2-[4-(4-methoxyphenyl)-2-oxo-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]acetamido}benzoate

IUPAC name

ethyl 4-{2-[4-(4-methoxyphenyl)-2-oxo-23-dihydro-1H-15-benzodiazepin-1-yl]acetamido}benzoate

SMILES

CCOC(c(cc1)ccc1NC(CN(c(cccc1)c1N=C(C1)c(cc2)ccc2OC)C1=O)=O)=O

InChI

InChI=1S/C27H25N3O5/c1-3-35-27(33)19-8-12-20(13-9-19)28-25(31)17-30-24-7-5-4-6-22(24)29-23(16-26(30)32)18-10-14-21(34-2)15-11-18/h4-15H,3,16-17H2,1-2H3,(H,28,31)

InChI Key

VTLZYBJNIUBAPV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27137034

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

471.51

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.635

Distribution Coefficient, logD

4.634

Water Solubility, LogSw

-4.26

Polar Surface Area

76.037

Acid Dissociation Constant (pKa)

10.82

Base Dissociation Constant (pKb)

-0.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.50

G353-0321 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G353-0321 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G353-0321?
Check Price and Availability of G353-0321, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G353-0321 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G353-0321
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G353-0321
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G353-0321 available by request