G353-0664 Screening compound: 2-[4-(4-ethylphenyl)-2-oxo-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]-N-(4-phenylbutan-2-yl)acetamide

G353-0664 Screening compound: 2-[4-(4-ethylphenyl)-2-oxo-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]-N-(4-phenylbutan-2-yl)acetamide
G353-0664 Screening compound: 2-[4-(4-ethylphenyl)-2-oxo-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]-N-(4-phenylbutan-2-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G353-0664
2-[4-(4-ethylphenyl)-2-oxo-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]-N-(4-phenylbutan-2-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G353-0664

Molecular Formula

C29H31N3O2 (C29 H31 N3 O2)

Compound Name

2-[4-(4-ethylphenyl)-2-oxo-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]-N-(4-phenylbutan-2-yl)acetamide

IUPAC name

2-[4-(4-ethylphenyl)-2-oxo-23-dihydro-1H-15-benzodiazepin-1-yl]-N-(4-phenylbutan-2-yl)acetamide

SMILES

CCc(cc1)ccc1C(C1)=Nc(cccc2)c2N(CC(NC(C)CCc2ccccc2)=O)C1=O

InChI

InChI=1S/C29H31N3O2/c1-3-22-15-17-24(18-16-22)26-19-29(34)32(27-12-8-7-11-25(27)31-26)20-28(33)30-21(2)13-14-23-9-5-4-6-10-23/h4-12,15-18,21H,3,13-14,19-20H2,1-2H3,(H,30,33)/t21-/m0/s1

InChI Key

VNSSBBZXDALECE-NRFANRHFSA-N

MDL Number (MFCD)

MFCD27137116

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

453.58

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.510

Distribution Coefficient, logD

5.510

Water Solubility, LogSw

-5.37

Polar Surface Area

48.503

Acid Dissociation Constant (pKa)

14.05

Base Dissociation Constant (pKb)

0.81

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

27.60

G353-0664 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Anti-HIV1 Library (19540 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G353-0664 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G353-0664?
Check Price and Availability of G353-0664, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G353-0664 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G353-0664
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G353-0664
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G353-0664 available by request