G353-0829 Screening compound: 2-[4-(2,4-dimethylphenyl)-2-oxo-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]-N-(3-ethylphenyl)acetamide

G353-0829 Screening compound: 2-[4-(2,4-dimethylphenyl)-2-oxo-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]-N-(3-ethylphenyl)acetamide
G353-0829 Screening compound: 2-[4-(2,4-dimethylphenyl)-2-oxo-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]-N-(3-ethylphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G353-0829
2-[4-(2,4-dimethylphenyl)-2-oxo-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]-N-(3-ethylphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G353-0829

Molecular Formula

C27H27N3O2 (C27 H27 N3 O2)

Compound Name

2-[4-(2,4-dimethylphenyl)-2-oxo-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]-N-(3-ethylphenyl)acetamide

IUPAC name

2-[4-(24-dimethylphenyl)-2-oxo-23-dihydro-1H-15-benzodiazepin-1-yl]-N-(3-ethylphenyl)acetamide

SMILES

CCc1cccc(NC(CN(c(cccc2)c2N=C(C2)c3c(C)cc(C)cc3)C2=O)=O)c1

InChI

InChI=1S/C27H27N3O2/c1-4-20-8-7-9-21(15-20)28-26(31)17-30-25-11-6-5-10-23(25)29-24(16-27(30)32)22-13-12-18(2)14-19(22)3/h5-15H,4,16-17H2,1-3H3,(H,28,31)

InChI Key

FRDQDUQXAZGWFR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15000930

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

425.53

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.709

Distribution Coefficient, logD

5.709

Water Solubility, LogSw

-5.37

Polar Surface Area

47.739

Acid Dissociation Constant (pKa)

12.71

Base Dissociation Constant (pKb)

1.16

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

G353-0829 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G353-0829 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G353-0829?
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What is the minimum amount of G353-0829 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G353-0829
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G353-0829
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G353-0829 available by request