G354-1258 Screening compound: 3-(4-methylphenyl)-1-[4-(pyridin-2-yl)piperazin-1-yl]-3-(1H-pyrrol-1-yl)propan-1-one

G354-1258 Screening compound: 3-(4-methylphenyl)-1-[4-(pyridin-2-yl)piperazin-1-yl]-3-(1H-pyrrol-1-yl)propan-1-one
G354-1258 Screening compound: 3-(4-methylphenyl)-1-[4-(pyridin-2-yl)piperazin-1-yl]-3-(1H-pyrrol-1-yl)propan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G354-1258
3-(4-methylphenyl)-1-[4-(pyridin-2-yl)piperazin-1-yl]-3-(1H-pyrrol-1-yl)propan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G354-1258

Molecular Formula

C23H26N4O (C23 H26 N4 O)

Compound Name

3-(4-methylphenyl)-1-[4-(pyridin-2-yl)piperazin-1-yl]-3-(1H-pyrrol-1-yl)propan-1-one

IUPAC name

3-(4-methylphenyl)-1-[4-(pyridin-2-yl)piperazin-1-yl]-3-(1H-pyrrol-1-yl)propan-1-one

SMILES

Cc1ccc(C(CC(N(CC2)CCN2c2ncccc2)=O)n2cccc2)cc1

InChI

InChI=1S/C23H26N4O/c1-19-7-9-20(10-8-19)21(25-12-4-5-13-25)18-23(28)27-16-14-26(15-17-27)22-6-2-3-11-24-22/h2-13,21H,14-18H2,1H3/t21-/m0/s1

InChI Key

SDADZHXYBFRDCO-NRFANRHFSA-N

MDL Number (MFCD)

MFCD15001210

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

374.49

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.971

Distribution Coefficient, logD

3.962

Water Solubility, LogSw

-3.87

Polar Surface Area

31.654

Acid Dissociation Constant (pKa)

22.46

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

30.40

G354-1258 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with G354-1258 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G354-1258?
Check Price and Availability of G354-1258, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G354-1258 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G354-1258
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G354-1258
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G354-1258 available by request