G357-0141 Screening compound: {2-methyl-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-yl}methyl 3-(3-chlorobenzamido)benzoate

G357-0141 Screening compound: {2-methyl-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-yl}methyl 3-(3-chlorobenzamido)benzoate
G357-0141 Screening compound: {2-methyl-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-yl}methyl 3-(3-chlorobenzamido)benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound G357-0141
{2-methyl-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-yl}methyl 3-(3-chlorobenzamido)benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G357-0141

Molecular Formula

C21H15ClN4O4S (C21 H15 ClN4 O4 S)

Compound Name

{2-methyl-5-oxo-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-yl}methyl 3-(3-chlorobenzamido)benzoate

IUPAC name

{2-methyl-5-oxo-5H-[134]thiadiazolo[32-a]pyrimidin-7-yl}methyl 3-(3-chlorobenzamido)benzoate

SMILES

CC(SC1=NC(COC(c2cccc(NC(c3cccc(Cl)c3)=O)c2)=O)=C2)=NN1C2=O

InChI

InChI=1S/C21H15ClN4O4S/c1-12-25-26-18(27)10-17(24-21(26)31-12)11-30-20(29)14-5-3-7-16(9-14)23-19(28)13-4-2-6-15(22)8-13/h2-10H,11H2,1H3,(H,23,28)

InChI Key

PPPDTLGVWSKUNA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15001760

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

454.89

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.204

Distribution Coefficient, logD

4.197

Water Solubility, LogSw

-4.60

Polar Surface Area

81.664

Acid Dissociation Constant (pKa)

9.74

Base Dissociation Constant (pKb)

5.47

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.50

G357-0141 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with G357-0141 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G357-0141?
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What is the minimum amount of G357-0141 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G357-0141
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G357-0141
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G357-0141 available by request