G357-1627 Screening compound: {5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 3-(2-methoxybenzamido)benzoate

G357-1627 Screening compound: {5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 3-(2-methoxybenzamido)benzoate
G357-1627 Screening compound: {5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 3-(2-methoxybenzamido)benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound G357-1627
{5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 3-(2-methoxybenzamido)benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G357-1627

Molecular Formula

C22H17N3O5S (C22 H17 N3 O5 S)

Compound Name

{5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 3-(2-methoxybenzamido)benzoate

IUPAC name

{5-oxo-5H-[13]thiazolo[32-a]pyrimidin-7-yl}methyl 3-(2-methoxybenzamido)benzoate

SMILES

COc(cccc1)c1C(Nc1cccc(C(OCC(N=C2SC=CN22)=CC2=O)=O)c1)=O

InChI

InChI=1S/C22H17N3O5S/c1-29-18-8-3-2-7-17(18)20(27)23-15-6-4-5-14(11-15)21(28)30-13-16-12-19(26)25-9-10-31-22(25)24-16/h2-12H,13H2,1H3,(H,23,27)

InChI Key

ZIIOZZKMZMRLFX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15002288

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

435.46

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.670

Distribution Coefficient, logD

2.665

Water Solubility, LogSw

-3.45

Polar Surface Area

77.773

Acid Dissociation Constant (pKa)

9.35

Base Dissociation Constant (pKb)

-2.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.10

G357-1627 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with G357-1627 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G357-1627?
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What is the minimum amount of G357-1627 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G357-1627
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G357-1627
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G357-1627 available by request