G357-1676 Screening compound: {5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 2-(3-methylbutanamido)benzoate

G357-1676 Screening compound: {5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 2-(3-methylbutanamido)benzoate
G357-1676 Screening compound: {5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 2-(3-methylbutanamido)benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound G357-1676
{5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 2-(3-methylbutanamido)benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G357-1676

Molecular Formula

C19H19N3O4S (C19 H19 N3 O4 S)

Compound Name

{5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 2-(3-methylbutanamido)benzoate

IUPAC name

{5-oxo-5H-[13]thiazolo[32-a]pyrimidin-7-yl}methyl 2-(3-methylbutanamido)benzoate

SMILES

CC(C)CC(Nc(cccc1)c1C(OCC(N=C1SC=CN11)=CC1=O)=O)=O

InChI

InChI=1S/C19H19N3O4S/c1-12(2)9-16(23)21-15-6-4-3-5-14(15)18(25)26-11-13-10-17(24)22-7-8-27-19(22)20-13/h3-8,10,12H,9,11H2,1-2H3,(H,21,23)

InChI Key

GZAVAUGXEYKCKR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15002301

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

385.44

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.129

Distribution Coefficient, logD

2.107

Water Solubility, LogSw

-3.04

Polar Surface Area

69.503

Acid Dissociation Constant (pKa)

8.68

Base Dissociation Constant (pKb)

-2.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.30

G357-1676 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G357-1676 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G357-1676?
Check Price and Availability of G357-1676, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G357-1676 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G357-1676
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G357-1676
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G357-1676 available by request