G357-1923 Screening compound: {3-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 2-(2-methylpropanamido)benzoate

G357-1923 Screening compound: {3-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 2-(2-methylpropanamido)benzoate
G357-1923 Screening compound: {3-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 2-(2-methylpropanamido)benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound G357-1923
{3-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 2-(2-methylpropanamido)benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G357-1923

Molecular Formula

C19H19N3O4S (C19 H19 N3 O4 S)

Compound Name

{3-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 2-(2-methylpropanamido)benzoate

IUPAC name

{3-methyl-5-oxo-5H-[13]thiazolo[32-a]pyrimidin-7-yl}methyl 2-(2-methylpropanamido)benzoate

SMILES

CC(C)C(Nc(cccc1)c1C(OCC(N=C1SC=C(C)N11)=CC1=O)=O)=O

InChI

InChI=1S/C19H19N3O4S/c1-11(2)17(24)21-15-7-5-4-6-14(15)18(25)26-9-13-8-16(23)22-12(3)10-27-19(22)20-13/h4-8,10-11H,9H2,1-3H3,(H,21,24)

InChI Key

CFCTXSKHVGBJMW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15002393

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

385.44

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.610

Distribution Coefficient, logD

2.593

Water Solubility, LogSw

-3.40

Polar Surface Area

69.381

Acid Dissociation Constant (pKa)

8.82

Base Dissociation Constant (pKb)

0.53

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.30

G357-1923 in Drug Discovery

Included in Screening Libraries

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G357-1923 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G357-1923?
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What is the minimum amount of G357-1923 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G357-1923
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G357-1923
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G357-1923 available by request