G357-4930 Screening compound: {2-methyl-7-oxo-7H-[1,2]oxazolo[2,3-a]pyrimidin-5-yl}methyl 3-(adamantane-1-amido)-4-chlorobenzoate

G357-4930 Screening compound: {2-methyl-7-oxo-7H-[1,2]oxazolo[2,3-a]pyrimidin-5-yl}methyl 3-(adamantane-1-amido)-4-chlorobenzoate
G357-4930 Screening compound: {2-methyl-7-oxo-7H-[1,2]oxazolo[2,3-a]pyrimidin-5-yl}methyl 3-(adamantane-1-amido)-4-chlorobenzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound G357-4930
{2-methyl-7-oxo-7H-[1,2]oxazolo[2,3-a]pyrimidin-5-yl}methyl 3-(adamantane-1-amido)-4-chlorobenzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G357-4930

Molecular Formula

C26H26ClN3O5 (C26 H26 ClN3 O5)

Compound Name

{2-methyl-7-oxo-7H-[1,2]oxazolo[2,3-a]pyrimidin-5-yl}methyl 3-(adamantane-1-amido)-4-chlorobenzoate

IUPAC name

{2-methyl-7-oxo-7H-[12]oxazolo[23-a]pyrimidin-5-yl}methyl 3-(adamantane-1-amido)-4-chlorobenzoate

SMILES

CC(ON12)=CC2=NC(COC(c(cc2)cc(NC(C3(CC(C4)C5)CC5CC4C3)=O)c2Cl)=O)=CC1=O

InChI

InChI=1S/C26H26ClN3O5/c1-14-4-22-28-19(9-23(31)30(22)35-14)13-34-24(32)18-2-3-20(27)21(8-18)29-25(33)26-10-15-5-16(11-26)7-17(6-15)12-26/h2-4,8-9,15-17H,5-7,10-13H2,1H3,(H,29,33)

InChI Key

SCLRCJJLSPRPAC-UHFFFAOYSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

495.96

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.870

Distribution Coefficient, logD

4.862

Water Solubility, LogSw

-4.93

Polar Surface Area

81.986

Acid Dissociation Constant (pKa)

9.17

Base Dissociation Constant (pKb)

3.25

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

46.20

G357-4930 in Drug Discovery

Included in Screening Libraries

GABA Library (7115 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Eye
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with G357-4930 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G357-4930?
Check Price and Availability of G357-4930, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G357-4930 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G357-4930
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G357-4930
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G357-4930 available by request