G361-0419 Screening compound: 2-[2-(4-methoxyphenyl)-4-oxo-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-5-yl]-N-[2-(2-methylpiperidin-1-yl)ethyl]acetamide

G361-0419 Screening compound: 2-[2-(4-methoxyphenyl)-4-oxo-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-5-yl]-N-[2-(2-methylpiperidin-1-yl)ethyl]acetamide
G361-0419 Screening compound: 2-[2-(4-methoxyphenyl)-4-oxo-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-5-yl]-N-[2-(2-methylpiperidin-1-yl)ethyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G361-0419
2-[2-(4-methoxyphenyl)-4-oxo-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-5-yl]-N-[2-(2-methylpiperidin-1-yl)ethyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G361-0419

Molecular Formula

C22H28N6O3 (C22 H28 N6 O3)

Compound Name

2-[2-(4-methoxyphenyl)-4-oxo-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-5-yl]-N-[2-(2-methylpiperidin-1-yl)ethyl]acetamide

IUPAC name

2-[2-(4-methoxyphenyl)-4-oxo-4H5H-pyrazolo[15-d][124]triazin-5-yl]-N-[2-(2-methylpiperidin-1-yl)ethyl]acetamide

SMILES

CC1N(CCNC(CN(C(c2c3)=O)N=Cn2nc3-c(cc2)ccc2OC)=O)CCCC1

InChI

InChI=1S/C22H28N6O3/c1-16-5-3-4-11-26(16)12-10-23-21(29)14-27-22(30)20-13-19(25-28(20)15-24-27)17-6-8-18(31-2)9-7-17/h6-9,13,15-16H,3-5,10-12,14H2,1-2H3,(H,23,29)/t16-/m0/s1

InChI Key

QQAZPTAMPNYWFK-INIZCTEOSA-N

MDL Number (MFCD)

MFCD15003146

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

424.5

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.150

Distribution Coefficient, logD

-0.607

Water Solubility, LogSw

-2.36

Polar Surface Area

77.435

Acid Dissociation Constant (pKa)

14.29

Base Dissociation Constant (pKb)

9.15

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

45.50

G361-0419 in Drug Discovery

Included in Screening Libraries

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G361-0419 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G361-0419?
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What is the minimum amount of G361-0419 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G361-0419
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G361-0419
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G361-0419 available by request