G361-0424 Screening compound: N-(3-{[1,4'-bipiperidin]-1'-yl}propyl)-2-[2-(4-methoxyphenyl)-4-oxo-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-5-yl]acetamide

G361-0424 Screening compound: N-(3-{[1,4'-bipiperidin]-1'-yl}propyl)-2-[2-(4-methoxyphenyl)-4-oxo-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-5-yl]acetamide
G361-0424 Screening compound: N-(3-{[1,4'-bipiperidin]-1'-yl}propyl)-2-[2-(4-methoxyphenyl)-4-oxo-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-5-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G361-0424
N-(3-{[1,4'-bipiperidin]-1'-yl}propyl)-2-[2-(4-methoxyphenyl)-4-oxo-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-5-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G361-0424

Molecular Formula

C27H37N7O3 (C27 H37 N7 O3)

Compound Name

N-(3-{[1,4'-bipiperidin]-1'-yl}propyl)-2-[2-(4-methoxyphenyl)-4-oxo-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-5-yl]acetamide

IUPAC name

N-(3-{[14'-bipiperidin]-1'-yl}propyl)-2-[2-(4-methoxyphenyl)-4-oxo-4H5H-pyrazolo[15-d][124]triazin-5-yl]acetamide

SMILES

COc(cc1)ccc1-c1nn(C=NN(CC(NCCCN(CC2)CCC2N2CCCCC2)=O)C2=O)c2c1

InChI

InChI=1S/C27H37N7O3/c1-37-23-8-6-21(7-9-23)24-18-25-27(36)33(29-20-34(25)30-24)19-26(35)28-12-5-13-31-16-10-22(11-17-31)32-14-3-2-4-15-32/h6-9,18,20,22H,2-5,10-17,19H2,1H3,(H,28,35)

InChI Key

OXFVGAHCKUPSHS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15003149

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

507.64

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.624

Distribution Coefficient, logD

-0.639

Water Solubility, LogSw

-2.37

Polar Surface Area

81.078

Acid Dissociation Constant (pKa)

16.02

Base Dissociation Constant (pKb)

9.66

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

55.60

G361-0424 in Drug Discovery

Included in Screening Libraries

3CLpro Library (4801 compounds)

CNS targets activity set (6557 compounds)

CORONAVIRUS Library (20774 compounds)

Human Receptors Annotated Library (5376 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G361-0424 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G361-0424?
Check Price and Availability of G361-0424, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G361-0424 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G361-0424
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G361-0424
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G361-0424 available by request