G362-0654 Screening compound: 1-(3-chloro-2-methylphenyl)-N-(2-ethoxyphenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide

G362-0654 Screening compound: 1-(3-chloro-2-methylphenyl)-N-(2-ethoxyphenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide
G362-0654 Screening compound: 1-(3-chloro-2-methylphenyl)-N-(2-ethoxyphenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G362-0654
1-(3-chloro-2-methylphenyl)-N-(2-ethoxyphenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G362-0654

Molecular Formula

C24H27ClN4O2 (C24 H27 ClN4 O2)

Compound Name

1-(3-chloro-2-methylphenyl)-N-(2-ethoxyphenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide

IUPAC name

1-(3-chloro-2-methylphenyl)-N-(2-ethoxyphenyl)-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide

SMILES

CCOc(cccc1)c1NC(c1c(C2CCNCC2)n(-c2cccc(Cl)c2C)nc1)=O

InChI

InChI=1S/C24H27ClN4O2/c1-3-31-22-10-5-4-8-20(22)28-24(30)18-15-27-29(21-9-6-7-19(25)16(21)2)23(18)17-11-13-26-14-12-17/h4-10,15,17,26H,3,11-14H2,1-2H3,(H,28,30)

InChI Key

UAQMZKWWLWEQDX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15003388

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

438.96

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.982

Distribution Coefficient, logD

0.501

Water Solubility, LogSw

-4.32

Polar Surface Area

54.517

Acid Dissociation Constant (pKa)

10.05

Base Dissociation Constant (pKb)

10.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

G362-0654 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with G362-0654 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G362-0654?
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What is the minimum amount of G362-0654 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G362-0654
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G362-0654
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G362-0654 available by request