G362-0952 Screening compound: 1-(4-chlorophenyl)-N-[(4-chlorophenyl)methyl]-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide

G362-0952 Screening compound: 1-(4-chlorophenyl)-N-[(4-chlorophenyl)methyl]-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide
G362-0952 Screening compound: 1-(4-chlorophenyl)-N-[(4-chlorophenyl)methyl]-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G362-0952
1-(4-chlorophenyl)-N-[(4-chlorophenyl)methyl]-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G362-0952

Molecular Formula

C22H22Cl2N4O (C22 H22 Cl2 N4 O)

Compound Name

1-(4-chlorophenyl)-N-[(4-chlorophenyl)methyl]-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide

IUPAC name

1-(4-chlorophenyl)-N-[(4-chlorophenyl)methyl]-5-(piperidin-4-yl)-1H-pyrazole-4-carboxamide

SMILES

O=C(c1c(C2CCNCC2)n(-c(cc2)ccc2Cl)nc1)NCc(cc1)ccc1Cl

InChI

InChI=1S/C22H22Cl2N4O/c23-17-3-1-15(2-4-17)13-26-22(29)20-14-27-28(19-7-5-18(24)6-8-19)21(20)16-9-11-25-12-10-16/h1-8,14,16,25H,9-13H2,(H,26,29)

InChI Key

QHGGEVYFBQKIQG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15003429

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

429.35

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.730

Distribution Coefficient, logD

0.249

Water Solubility, LogSw

-4.40

Polar Surface Area

49.627

Acid Dissociation Constant (pKa)

11.54

Base Dissociation Constant (pKb)

10.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

G362-0952 in Drug Discovery

Included in Screening Libraries

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Targets:
  • Ion Channels
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G362-0952 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G362-0952?
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What is the minimum amount of G362-0952 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G362-0952
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G362-0952
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G362-0952 available by request