G364-0450 Screening compound: 2-[6-(4-chlorobenzyl)-1,1-dioxo-1lambda~6~,2,6-thiadiazinan-2-yl]-N~1~-(2-chlorophenyl)acetamide

G364-0450 Screening compound: 2-[6-(4-chlorobenzyl)-1,1-dioxo-1lambda~6~,2,6-thiadiazinan-2-yl]-N~1~-(2-chlorophenyl)acetamide
G364-0450 Screening compound: 2-[6-(4-chlorobenzyl)-1,1-dioxo-1lambda~6~,2,6-thiadiazinan-2-yl]-N~1~-(2-chlorophenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G364-0450
2-[6-(4-chlorobenzyl)-1,1-dioxo-1lambda~6~,2,6-thiadiazinan-2-yl]-N~1~-(2-chlorophenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G364-0450

Molecular Formula

C18H19Cl2N3O3S (C18 H19 Cl2 N3 O3 S)

Compound Name

2-[6-(4-chlorobenzyl)-1,1-dioxo-1lambda~6~,2,6-thiadiazinan-2-yl]-N~1~-(2-chlorophenyl)acetamide

IUPAC name

N-(2-chlorophenyl)-2-{6-[(4-chlorophenyl)methyl]-11-dioxo-1lambda626-thiadiazinan-2-yl}acetamide

SMILES

O=C(CN(CCCN1Cc(cc2)ccc2Cl)S1(=O)=O)Nc(cccc1)c1Cl

InChI

InChI=1S/C18H19Cl2N3O3S/c19-15-8-6-14(7-9-15)12-22-10-3-11-23(27(22,25)26)13-18(24)21-17-5-2-1-4-16(17)20/h1-2,4-9H,3,10-13H2,(H,21,24)

InChI Key

BRFQMDVEJDRRSP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15003516

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

428.34

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.084

Distribution Coefficient, logD

3.084

Water Solubility, LogSw

-3.35

Polar Surface Area

58.830

Acid Dissociation Constant (pKa)

10.89

Base Dissociation Constant (pKb)

-1.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

G364-0450 in Drug Discovery

Included in Screening Libraries

Human Proteases Annotated Library (2868 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with G364-0450 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G364-0450?
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What is the minimum amount of G364-0450 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G364-0450
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G364-0450
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G364-0450 available by request