G364-1232 Screening compound: 2-[5-(2-fluorobenzyl)-1,1-dioxo-1lambda~6~,2,5-thiadiazolan-2-yl]-N~1~-mesitylacetamide

G364-1232 Screening compound: 2-[5-(2-fluorobenzyl)-1,1-dioxo-1lambda~6~,2,5-thiadiazolan-2-yl]-N~1~-mesitylacetamide
G364-1232 Screening compound: 2-[5-(2-fluorobenzyl)-1,1-dioxo-1lambda~6~,2,5-thiadiazolan-2-yl]-N~1~-mesitylacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G364-1232
2-[5-(2-fluorobenzyl)-1,1-dioxo-1lambda~6~,2,5-thiadiazolan-2-yl]-N~1~-mesitylacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G364-1232

Molecular Formula

C20H24FN3O3S (C20 H24 FN3 O3 S)

Compound Name

2-[5-(2-fluorobenzyl)-1,1-dioxo-1lambda~6~,2,5-thiadiazolan-2-yl]-N~1~-mesitylacetamide

IUPAC name

2-{5-[(2-fluorophenyl)methyl]-11-dioxo-1lambda625-thiadiazolidin-2-yl}-N-(246-trimethylphenyl)acetamide

SMILES

Cc(cc1C)cc(C)c1NC(CN(CCN1Cc(cccc2)c2F)S1(=O)=O)=O

InChI

InChI=1S/C20H24FN3O3S/c1-14-10-15(2)20(16(3)11-14)22-19(25)13-24-9-8-23(28(24,26)27)12-17-6-4-5-7-18(17)21/h4-7,10-11H,8-9,12-13H2,1-3H3,(H,22,25)

InChI Key

KZAHAYMMFAVIRS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15003582

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

405.49

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.032

Distribution Coefficient, logD

3.032

Water Solubility, LogSw

-3.14

Polar Surface Area

58.498

Acid Dissociation Constant (pKa)

12.18

Base Dissociation Constant (pKb)

1.00

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.00

G364-1232 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with G364-1232 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G364-1232?
Check Price and Availability of G364-1232, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G364-1232 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G364-1232
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G364-1232
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G364-1232 available by request