G364-1867 Screening compound: N~1~-(1,3-benzodioxol-5-yl)-2-[5-(2-chloro-4-fluorobenzyl)-1,1-dioxo-1lambda~6~,2,5-thiadiazolan-2-yl]acetamide

G364-1867 Screening compound: N~1~-(1,3-benzodioxol-5-yl)-2-[5-(2-chloro-4-fluorobenzyl)-1,1-dioxo-1lambda~6~,2,5-thiadiazolan-2-yl]acetamide
G364-1867 Screening compound: N~1~-(1,3-benzodioxol-5-yl)-2-[5-(2-chloro-4-fluorobenzyl)-1,1-dioxo-1lambda~6~,2,5-thiadiazolan-2-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G364-1867
N~1~-(1,3-benzodioxol-5-yl)-2-[5-(2-chloro-4-fluorobenzyl)-1,1-dioxo-1lambda~6~,2,5-thiadiazolan-2-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G364-1867

Molecular Formula

C18H17ClFN3O5S (C18 H17 ClFN3 O5 S)

Compound Name

N~1~-(1,3-benzodioxol-5-yl)-2-[5-(2-chloro-4-fluorobenzyl)-1,1-dioxo-1lambda~6~,2,5-thiadiazolan-2-yl]acetamide

IUPAC name

N-(2H-13-benzodioxol-5-yl)-2-{5-[(2-chloro-4-fluorophenyl)methyl]-11-dioxo-1lambda625-thiadiazolidin-2-yl}acetamide

SMILES

O=C(CN(CCN1Cc(ccc(F)c2)c2Cl)S1(=O)=O)Nc(cc1)cc2c1OCO2

InChI

InChI=1S/C18H17ClFN3O5S/c19-15-7-13(20)2-1-12(15)9-22-5-6-23(29(22,25)26)10-18(24)21-14-3-4-16-17(8-14)28-11-27-16/h1-4,7-8H,5-6,9-11H2,(H,21,24)

InChI Key

LTDYRWCITRVPQK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15003660

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

441.87

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.936

Distribution Coefficient, logD

2.936

Water Solubility, LogSw

-3.47

Polar Surface Area

77.010

Acid Dissociation Constant (pKa)

11.47

Base Dissociation Constant (pKb)

0.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

G364-1867 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Mechanism of action:
  • Epigenetic
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with G364-1867 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G364-1867?
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What is the minimum amount of G364-1867 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G364-1867
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G364-1867
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G364-1867 available by request