G365-0002 Screening compound: 1-{1H,4H,5H-benzo[g]indazole-3-carbonyl}-4-benzylpiperidine

G365-0002 Screening compound: 1-{1H,4H,5H-benzo[g]indazole-3-carbonyl}-4-benzylpiperidine
G365-0002 Screening compound: 1-{1H,4H,5H-benzo[g]indazole-3-carbonyl}-4-benzylpiperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound G365-0002
1-{1H,4H,5H-benzo[g]indazole-3-carbonyl}-4-benzylpiperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G365-0002

Molecular Formula

C24H25N3O (C24 H25 N3 O)

Compound Name

1-{1H,4H,5H-benzo[g]indazole-3-carbonyl}-4-benzylpiperidine

IUPAC name

1-{1H4H5H-benzo[g]indazole-3-carbonyl}-4-benzylpiperidine

SMILES

O=C(c1n[nH]c-2c1CCc1c2cccc1)N1CCC(Cc2ccccc2)CC1

InChI

InChI=1S/C24H25N3O/c28-24(27-14-12-18(13-15-27)16-17-6-2-1-3-7-17)23-21-11-10-19-8-4-5-9-20(19)22(21)25-26-23/h1-9,18H,10-16H2,(H,25,26)

InChI Key

UMXDVGZCFPLZJY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15003680

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

371.48

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.061

Distribution Coefficient, logD

5.061

Water Solubility, LogSw

-4.95

Polar Surface Area

40.657

Acid Dissociation Constant (pKa)

6.35

Base Dissociation Constant (pKb)

-1.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

G365-0002 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G365-0002 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G365-0002?
Check Price and Availability of G365-0002, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G365-0002 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G365-0002
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G365-0002
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G365-0002 available by request