G365-0025 Screening compound: 1-{1H,4H,5H-benzo[g]indazole-3-carbonyl}-4-(4-chlorophenyl)piperazine

G365-0025 Screening compound: 1-{1H,4H,5H-benzo[g]indazole-3-carbonyl}-4-(4-chlorophenyl)piperazine
G365-0025 Screening compound: 1-{1H,4H,5H-benzo[g]indazole-3-carbonyl}-4-(4-chlorophenyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G365-0025
1-{1H,4H,5H-benzo[g]indazole-3-carbonyl}-4-(4-chlorophenyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G365-0025

Molecular Formula

C22H21ClN4O (C22 H21 ClN4 O)

Compound Name

1-{1H,4H,5H-benzo[g]indazole-3-carbonyl}-4-(4-chlorophenyl)piperazine

IUPAC name

1-{1H4H5H-benzo[g]indazole-3-carbonyl}-4-(4-chlorophenyl)piperazine

SMILES

O=C(c1n[nH]c-2c1CCc1c2cccc1)N(CC1)CCN1c(cc1)ccc1Cl

InChI

InChI=1S/C22H21ClN4O/c23-16-6-8-17(9-7-16)26-11-13-27(14-12-26)22(28)21-19-10-5-15-3-1-2-4-18(15)20(19)24-25-21/h1-4,6-9H,5,10-14H2,(H,24,25)

InChI Key

ZJJKNGYURQCEDC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15003697

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

392.89

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.442

Distribution Coefficient, logD

4.442

Water Solubility, LogSw

-4.80

Polar Surface Area

44.189

Acid Dissociation Constant (pKa)

6.35

Base Dissociation Constant (pKb)

5.38

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

G365-0025 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with G365-0025 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G365-0025?
Check Price and Availability of G365-0025, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G365-0025 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G365-0025
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G365-0025
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G365-0025 available by request