G365-0223 Screening compound: ethyl 3-{7-methoxy-1H,4H,5H-benzo[g]indazole-3-amido}benzoate

G365-0223 Screening compound: ethyl 3-{7-methoxy-1H,4H,5H-benzo[g]indazole-3-amido}benzoate
G365-0223 Screening compound: ethyl 3-{7-methoxy-1H,4H,5H-benzo[g]indazole-3-amido}benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound G365-0223
ethyl 3-{7-methoxy-1H,4H,5H-benzo[g]indazole-3-amido}benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G365-0223

Molecular Formula

C22H21N3O4 (C22 H21 N3 O4)

Compound Name

ethyl 3-{7-methoxy-1H,4H,5H-benzo[g]indazole-3-amido}benzoate

IUPAC name

ethyl 3-{7-methoxy-1H4H5H-benzo[g]indazole-3-amido}benzoate

SMILES

CCOC(c1cc(NC(c2n[nH]c-3c2CCc2c3ccc(OC)c2)=O)ccc1)=O

InChI

InChI=1S/C22H21N3O4/c1-3-29-22(27)14-5-4-6-15(11-14)23-21(26)20-18-9-7-13-12-16(28-2)8-10-17(13)19(18)24-25-20/h4-6,8,10-12H,3,7,9H2,1-2H3,(H,23,26)(H,24,25)

InChI Key

SJMJZTFAXAHQIQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15003819

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

391.43

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.824

Distribution Coefficient, logD

4.824

Water Solubility, LogSw

-4.54

Polar Surface Area

75.669

Acid Dissociation Constant (pKa)

6.15

Base Dissociation Constant (pKb)

-0.79

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

G365-0223 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Anti-Aging Library (44940 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Glucocorticoid receptors Library (4806 compounds)

Protein-Protein Interaction Library (218420 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Mechanism of action:
  • Epigenetic
  • Receptor's ligands
  • PPI modulators
  • Receptor's ligands
Targets:
  • Nuclear receptors
  • Kinases

References: we are preparing a list of scientific research reports with G365-0223 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G365-0223?
Check Price and Availability of G365-0223, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G365-0223 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G365-0223
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G365-0223
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G365-0223 available by request