G365-0362 Screening compound: N-({1-[(3-fluorophenyl)methyl]piperidin-4-yl}methyl)-7-methoxy-1H,4H,5H-benzo[g]indazole-3-carboxamide

G365-0362 Screening compound: N-({1-[(3-fluorophenyl)methyl]piperidin-4-yl}methyl)-7-methoxy-1H,4H,5H-benzo[g]indazole-3-carboxamide
G365-0362 Screening compound: N-({1-[(3-fluorophenyl)methyl]piperidin-4-yl}methyl)-7-methoxy-1H,4H,5H-benzo[g]indazole-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G365-0362
N-({1-[(3-fluorophenyl)methyl]piperidin-4-yl}methyl)-7-methoxy-1H,4H,5H-benzo[g]indazole-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G365-0362

Molecular Formula

C26H29FN4O2 (C26 H29 FN4 O2)

Compound Name

N-({1-[(3-fluorophenyl)methyl]piperidin-4-yl}methyl)-7-methoxy-1H,4H,5H-benzo[g]indazole-3-carboxamide

IUPAC name

N-({1-[(3-fluorophenyl)methyl]piperidin-4-yl}methyl)-7-methoxy-1H4H5H-benzo[g]indazole-3-carboxamide

SMILES

COc(cc1)cc(CC2)c1-c1c2c(C(NCC2CCN(Cc3cccc(F)c3)CC2)=O)n[nH]1

InChI

InChI=1S/C26H29FN4O2/c1-33-21-6-8-22-19(14-21)5-7-23-24(22)29-30-25(23)26(32)28-15-17-9-11-31(12-10-17)16-18-3-2-4-20(27)13-18/h2-4,6,8,13-14,17H,5,7,9-12,15-16H2,1H3,(H,28,32)(H,29,30)

InChI Key

UEXGYEUQIBXZRT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15003929

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

448.54

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.378

Distribution Coefficient, logD

2.455

Water Solubility, LogSw

-4.35

Polar Surface Area

59.970

Acid Dissociation Constant (pKa)

6.47

Base Dissociation Constant (pKb)

9.32

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.50

G365-0362 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

MCL1 Targeted Library (12200 compounds)

Protein-Protein Interaction Library (218420 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G365-0362 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G365-0362?
Check Price and Availability of G365-0362, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G365-0362 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G365-0362
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G365-0362
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G365-0362 available by request