G368-0035 Screening compound: N-(3-methylphenyl)-4-oxo-3,4-dihydrospiro[1,3-benzoxazine-2,4'-piperidine]-1'-carboxamide

G368-0035 Screening compound: N-(3-methylphenyl)-4-oxo-3,4-dihydrospiro[1,3-benzoxazine-2,4'-piperidine]-1'-carboxamide
G368-0035 Screening compound: N-(3-methylphenyl)-4-oxo-3,4-dihydrospiro[1,3-benzoxazine-2,4'-piperidine]-1'-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G368-0035
N-(3-methylphenyl)-4-oxo-3,4-dihydrospiro[1,3-benzoxazine-2,4'-piperidine]-1'-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G368-0035

Molecular Formula

C20H21N3O3 (C20 H21 N3 O3)

Compound Name

N-(3-methylphenyl)-4-oxo-3,4-dihydrospiro[1,3-benzoxazine-2,4'-piperidine]-1'-carboxamide

IUPAC name

N-(3-methylphenyl)-4-oxo-34-dihydrospiro[13-benzoxazine-24'-piperidine]-1'-carboxamide

SMILES

Cc1cccc(NC(N(CC2)CCC2(N2)Oc(cccc3)c3C2=O)=O)c1

InChI

InChI=1S/C20H21N3O3/c1-14-5-4-6-15(13-14)21-19(25)23-11-9-20(10-12-23)22-18(24)16-7-2-3-8-17(16)26-20/h2-8,13H,9-12H2,1H3,(H,21,25)(H,22,24)

InChI Key

GWYZWIVWWOTUFQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15004564

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

351.41

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.586

Distribution Coefficient, logD

2.586

Water Solubility, LogSw

-3.30

Polar Surface Area

57.942

Acid Dissociation Constant (pKa)

13.54

Base Dissociation Constant (pKb)

-0.13

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.00

G368-0035 in Drug Discovery

Included in Screening Libraries

3CLpro Library (4801 compounds)

CORONAVIRUS Library (20774 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with G368-0035 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G368-0035?
Check Price and Availability of G368-0035, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G368-0035 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G368-0035
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G368-0035
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G368-0035 available by request