G370-0253 Screening compound: N-{4-[({[1-(4-methylbenzyl)-4-piperidyl]methyl}amino)carbonyl]phenyl}-5,6-dihydro-1,4-oxathiine-2-carboxamide

G370-0253 Screening compound: N-{4-[({[1-(4-methylbenzyl)-4-piperidyl]methyl}amino)carbonyl]phenyl}-5,6-dihydro-1,4-oxathiine-2-carboxamide
G370-0253 Screening compound: N-{4-[({[1-(4-methylbenzyl)-4-piperidyl]methyl}amino)carbonyl]phenyl}-5,6-dihydro-1,4-oxathiine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G370-0253
N-{4-[({[1-(4-methylbenzyl)-4-piperidyl]methyl}amino)carbonyl]phenyl}-5,6-dihydro-1,4-oxathiine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G370-0253

Molecular Formula

C26H31N3O3S (C26 H31 N3 O3 S)

Compound Name

N-{4-[({[1-(4-methylbenzyl)-4-piperidyl]methyl}amino)carbonyl]phenyl}-5,6-dihydro-1,4-oxathiine-2-carboxamide

IUPAC name

N-{4-[({1-[(4-methylphenyl)methyl]piperidin-4-yl}methyl)carbamoyl]phenyl}-56-dihydro-14-oxathiine-2-carboxamide

SMILES

Cc1ccc(CN2CCC(CNC(c(cc3)ccc3NC(C3=CSCCO3)=O)=O)CC2)cc1

InChI

InChI=1S/C26H31N3O3S/c1-19-2-4-21(5-3-19)17-29-12-10-20(11-13-29)16-27-25(30)22-6-8-23(9-7-22)28-26(31)24-18-33-15-14-32-24/h2-9,18,20H,10-17H2,1H3,(H,27,30)(H,28,31)

InChI Key

LLIRXQAXVRDZLT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15004727

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

465.62

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.411

Distribution Coefficient, logD

0.690

Water Solubility, LogSw

-3.57

Polar Surface Area

61.104

Acid Dissociation Constant (pKa)

7.74

Base Dissociation Constant (pKb)

10.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.46

G370-0253 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G370-0253 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G370-0253?
Check Price and Availability of G370-0253, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G370-0253 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G370-0253
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G370-0253
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G370-0253 available by request