G371-0110 Screening compound: 4-[(4-bromo-2-fluorophenyl)methyl]-2-ethoxy-3H,4H-pyrido[2,3-b]pyrazin-3-one

G371-0110 Screening compound: 4-[(4-bromo-2-fluorophenyl)methyl]-2-ethoxy-3H,4H-pyrido[2,3-b]pyrazin-3-one
G371-0110 Screening compound: 4-[(4-bromo-2-fluorophenyl)methyl]-2-ethoxy-3H,4H-pyrido[2,3-b]pyrazin-3-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G371-0110
4-[(4-bromo-2-fluorophenyl)methyl]-2-ethoxy-3H,4H-pyrido[2,3-b]pyrazin-3-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G371-0110

Molecular Formula

C16H13BrFN3O2 (C16 H13 BrFN3 O2)

Compound Name

4-[(4-bromo-2-fluorophenyl)methyl]-2-ethoxy-3H,4H-pyrido[2,3-b]pyrazin-3-one

IUPAC name

4-[(4-bromo-2-fluorophenyl)methyl]-2-ethoxy-3H4H-pyrido[23-b]pyrazin-3-one

SMILES

CCOC1=Nc2cccnc2N(Cc(ccc(Br)c2)c2F)C1=O

InChI

InChI=1S/C16H13BrFN3O2/c1-2-23-15-16(22)21(14-13(20-15)4-3-7-19-14)9-10-5-6-11(17)8-12(10)18/h3-8H,2,9H2,1H3

InChI Key

ACVYHZRYPJVEFP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15005082

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

378.2

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.457

Distribution Coefficient, logD

3.457

Water Solubility, LogSw

-3.65

Polar Surface Area

41.932

Acid Dissociation Constant (pKa)

22.79

Base Dissociation Constant (pKb)

1.94

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.80

G371-0110 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with G371-0110 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G371-0110?
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What is the minimum amount of G371-0110 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G371-0110
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G371-0110
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G371-0110 available by request